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Wednesday, June 21, 2017

Researchers found Experimental Ebola vaccine safe in human

A new Ebola vaccine has been found to be safe for humans, according to the results of an early clinical trial developed at the Canadian National Microbiology Laboratory of the Public Health Agency of Canada. 

The researchers also found that high antibodies were present in participants six months after immunisation with the experimental VSV (vesicular stomatitis virus)-Ebola vaccine.

The trial involved 40 healthy people aged 18 to 65 years and looked at the safety of the vaccine and the lowest dose required for an immune response after injection with one of three doses. Out of the 40 people, 30 participants received the vaccine and 10 received placebo injections. The researchers found that adverse events were mild to moderate, with only three severe reactions, including headache, diarrhea and fatigue, which were completely resolved. 

"The results of this trial were positive and very promising; all 3 dose levels of the VSV [vesicular stomatitis virus] Ebola vaccine were well-tolerated by participants, and no safety concerns were identified," says Dr. May ElSherif.

This study, published in Canadian Medical Association Journal (CMAJ) shows the importance of further investigation.

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